Nutrience Care+ Calm & Comfort Dry Dog Food. Nutrience Care Calm & Comfort is specifically formulated for dogs with hyperactivity and anxiety-related behaviors and sensitivities. This food helps to reduce signs of anxiety in dogs and stimulates the production of serotonin and dopamine which are important for mood regulation, alleviating dominance aggression signs in dogs. Dopamine is also an important nutrient for attention and focus for easier training. In addition to caring for your dog’s special needs, we’ve taken great strides to ensure their care is delivered in the form of a high-quality, gluten-free diet, made of healthy, wholesome ingredients. The importance of a good digestive system and healthy gut flora cannot be overstated when it comes to proper nutrient absorption. That’s why every bag of Nutrience Care® includes Digestiboost – made with ingredients like pumpkin, chicory root, turmeric and ginger to help support overall gut health. Helps Reduce Signs of Anxiety: Hydrolyzed casein, or alpha-casozepine is a bioactive peptide originating from a protein in cow’s milk, which produces a naturally calming effect and helps reduce signs of anxiety in dogs. Increased Serotonin: Inclusion of l-tryptophan: an amino acid required for serotonin production studied for its role in mood regulation and alleviating dominance aggression signs in dogs. Increased Dopamine: Inclusion of l-tyrosine: an amino acid required for dopamine production, a nutrient important for attention and focus, and ease training. Recommended for: Puppies, adult and senior dogs Lactating and pregnant dogs Management of stress and anxiety-related issues Available Sizes: 2.27 kg / 10 kg